Ocular surface squamous neoplasia
Medical treatment
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| OSSN prior to treatment with Mitomycin C. See below for results of treatment. |
Some OSSN can be treated by chemotherapy with Mitomycin C eyedrops.
Mitomycin C (MMC)
MMC is a drug used to treat some types of cancer and to reduce scarring after surgery. It is regularily used in a number of eye conditions including glaucoma surgery. MMC has been used to treat OSSN for the last decade.
MMC in OSSN
MMC is used to treat OSSN when:
- Patients decline surgery
- Tumours are small
- Surgery was unsuccessful in removing all the tumour
- The tumour is aggressive or invasive
- Surgical removal of a large tumour would threaten the viability of the eye
Treatment with MMC
Same eye as above, following successful treatment of OSSN with Mitomycin C.
Patients with suspected or confirmed OSSN typically receive a course of treatment:
- Four times a day
- Week on, week off
- For two to four cycles
Risks of MMC
The risks of MMC therapy are very low but include:
- Failure to achieve eradication of the tumour
- Irritation of the surface of the eye