Ocular surface squamous neoplasia

What is it?
Ocular surface squamous neoplasia

Ocular surface squamous neoplasia (OSSN) is an uncommon malignancy of the conjunctiva and cornea. It can be thought of as a 'skin cancer' of the eye. 

 

Clinical features

Typical features of OSSN include:

  • Arises near the limbus (junction of cornea and sclera)
  • Most commonly found at the 3 or 9 o'clock position
  • Fleshy, gelatinous appearance
  • Round or oval shape
  • Irregular blood vessel pattern
  • Minimal symptoms
  • Slow growing

 

Who gets OSSN?      

OSSN is more common in patients who are:

  • Older
  • Have had significant sunlight exposure
  • Are taking immune system supressing drugs

 

Differences between OSSN and pterygia

OSSN can mimic a pterygium. In general pterygia:

  • Occur at a younger age
  • Are more triangular in shape
  • Appear flatter rather than gelatinous
  • Have more linear blood vessels
  • Cause more symptoms